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FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012
NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022
EXHIBIT E
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NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022
SUPREME COURT OF THE STATE OF NEW YORK
COUNTY OF SUFFOLK
Index Number: 26910/12
xxxxxx xxxxxxxx, on behalf of C S , an
infant under the age of 18, and xxxxxx xxxxxxxx, PLAINTIFF’S EXPERT
Individually, WITNESS EXCHANGE
CRANIOFACIAL
Plaintiffs, RECONSTRUCTIVE &
PLASTIC SURGERY
-against-
RONALD J. TADEO, M.D., RICHARD PITCH, M.D.,
SCOTT BERLIN, M.D., SHORE PSYCHIATRIC CENTER,
FAMILY PSYCHOLOGY OF LONG ISLAND, BERLIN
OBGYN ASSOCIATES, JANSSEN PHARMACEUTICALS,
INC. and ZYDUS PHARMACEUTICALS (USA), INC.,
Defendants.
Plaintiffs, by their attorneys, NAPOLI SHKOLNIK PLLC, as and for an Expert Witness
Disclosure pursuant to CPLR §3101(d), reserves the right to call the following witness at the
time of trial:
Russell R. Reid, M.D., Ph.D.
The University of Chicago Medical Center
5841 S. Maryland Avenue
Chicago, IL 60637
1. Annexed hereto is the curriculum vitae of Russell R. Reid, M.D., Ph.D. which sets
out his qualifications, educational background, training, membership in societies, academic
appointments and committees and publication and teaching experience.
2. In particular, Dr. Reid is an experienced craniofacial plastic and reconstructive
surgeon who is licensed to practice medicine in the state of Illinois. He is board certified by the
American Board of Plastic Surgery. He received his medical degree Northwestern University in
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1998, where he also earned a Ph.D. in Pathology. He completed his residency and fellowship in
Plastic Surgery at the University of Chicago/McGraw Medical Center in 2005. He completed a
fellowship in craniofacial surgery at the University of Pennsylvania in 2006.
3. Dr. Reid specializes in the field of pediatric craniofacial reconstructive and plastic
surgery. He is a Director of the Cleft Lip and Palate Team and Director of the Laboratory and
Director of the Craniofacial Anomalies Multidisciplinary Program both with the University of
Chicago Medical Center, where he also serves as a Professor of Surgery and Pediatrics.
4. Dr. Reid is expected to opine at the time of trial, on behalf of infant plaintiff,
C S , with regard to the permanent disability of plaintiff, as a result of
teratogenic injuries he sustained in utero from Topamax/topiramate, which resulted in a bilateral
cleft lip and palate, developmental delays, hearing delays, and severe mental anguish and
distress. More particularly, Dr. Reid is expected to testify pertaining to the plaintiff’s physical,
ailments, personal injuries with respect to their implications on C craniofacial growth and
development, and his need for future treatment including surgery, and how they are all sequelae
of the cleft lip and cleft palate C developed in utero.
5. Dr. Reid will opine that due to the subject malpractice, plaintiff, C
S , has suffered serious, permanent and debilitating personal injuries, which adversely
affect plaintiff’s past, present and future health status and mental health status, which will
continue into adulthood and negatively affect quality of life.
6. Dr. Reid will opine in regards to the medical diagnoses and conclusions, relevant
to the plaintiff’s health status, as a result of the injuries in utero he sustained which are the
subject of this lawsuit.
7. Dr. Reid is expected to opine on how craniofacial defects begin in embryonic
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development. He will testify on how the fetal palate, lips, nose, and jaw develop in the first few
weeks of pregnancy, and the effects of teratogens, including Topamax/topiramate, on said
development. It is Dr. Reid’s opinion that Topamax/topiramate has the ability to significantly
alter the activity of important cell signaling molecules (proteins), which can be translated to the
context of the developing embryo.
8. Dr. Reis is expected to opine that C craniofacial malformations, specifically
cleft lip palate consistent with· abnormal craniofacial development due to perturbations of select
signaling.· pathways during embryogenesis, and that development of the craniofacies requires
strict coordination of cellular activity, which is controlled by cell-signaling proteins to regulate
cellular communication. He will opine that Topiramate ultimately impairs embryonic cellular
differentiation and growth as it is shown to interfere and disrupt these proteins and that such a
disruption can lead to the induction of congenital defects.
9. Dr. Reid will opine that craniofacial defects are among the known congenital
malformations occurring at a higher prevalence in children exposed to maternal use of
topiramate. Oral clefts, particularly cleft lip and. palate, are craniofacial defects known to ·occur
due to alteration of the activity of signaling proteins.
10. Dr. Reid will opine that C cleft lip and palate ate consistent with the
congenital malformations seen in children born to mothers who ingested Topamax/topiramate
during pregnancy. This is supported by the facts that C mother ingested this medication
during the first trimester and the lack of other statistically significant comorbidities.
11. Dr. Reid’s opinion is based on his extensive education, knowledge of and
expertise in plastic and reconstructive craniofacial surgery, his experience treating children with
cleft lips and palates, his academic research on the subject, all medical records relevant in this
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matter, all pleadings and documents exchanged in this matter, as well as deposition testimony.
12. Dr. Reid will opine that C S will continue to have permanent
deficits that will require medical treatment and procedures for the foreseeable future.
13. Dr. Reid will opine that Topamax/topiramate is causally associated with oral
clefts in infants born to mothers who ingest this medication during the first trimester and in
particular that C S injuries are of a direct causal relationship the subject
malpractice.
14. Dr. Reid will also rebut defendants’ medical expert’s testimony and will comment
on any and all evidence and exhibits used at the time of trial.
15. Plaintiff reserves his right to submit additional expert information when and if it
becomes available to plaintiffs and their counsel, including a supplemental report.
Dated: Melville, New York
July 12, 2022
Yours, etc.
___________________________
xxxxxx xxxxxxx
NAPOLI SHKOLNIK PLLC
Attorneys for Plaintiff
400 Broadhollow Road, Suite 305
Melville, NY 11747
(212) 397-1000
To:
MARTIN CLEARWATER & BELL LLP
Attorneys for Defendants
RONALD J. TADEO, M.D. and SHORE PSYCHIATRIC CENTER
90 Merrick Ave, Suite 401
East Meadow, NY 11554
516-222-8500
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CURRICULUM VITAE
RusseiiRbger Reid, MtJ PhD
Associate Professor of Surgery
· Bernard Sarnat Scholar of Craniofacial Research
Director~ Cleft Lip and Palate Team . · ·.· .
·Department of Surgery/Section of Plastic and Reconstructive Surgery
The University of Chicago Medical Center · .·. .·· ·
5841 South Maryland Avenue, M/C 6035, Chicago, IL 60637
Tel.: (773)-702~6302 · · ·
. (773)~ 702-8985
Facsimile: (773)-702-1634 .
Email: rreid@surgery:bsd.uchicago.edu
Assistant ~r()f~ssor of. Pediatrics, 1he University of Chicago ~edical Center
Attending Surgeon, Advocate Lutheran General Childreri'sHospital
M:Tbe~, pepa~~ment~f Surg~ry qu~lity Subcom~ittee (University of Chi~ago)
Member,' Edl1catiop Cortill1ittee,American Society of Maxillofacial Surgeons
Member, Research Committee, American Society ofAesthetic Plastic Surgeons
Invited Reviewer, Cleft Palate Craniofacial journal ·
Invited Reviewer,journalof Pediatric Neurosurgery
· Education Institution and Field
B.A. Yale lJnivet~ity, NewHiven, ConnectiCut
Bachelor of Arts in Literature (Magna Cum Laude)
Distinction in the Major, May, 1990
M.D. Harvard Medieal School, Boston, MA, June,1998
Ph.D, Harvard Medical School, Boston, MA
Department of Pathology(Iminunology), advisor:
~ichae.rc. Carroll, Pp.D. ancl the late
Fred s. Rosen, M.D., June,1998
Internship /Residency Int:~ratecl Prog~~m in Plastic Surgery
Northwestern UniversityjMcGaw Medical Center
Chicago, IL (1998-2005)
Chairman: Thomas A. Mustoe, M.D. F.A.C.S.
Fellowship Craniofacial Fellow, University of Pennsylvania
Philadelphia, PA (2005-2006)
Program Director: Scott P. Bartlett, M.D. F.A.C.S
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Training and Employment
1992-1996: Predpetoral FeHlo\JV,Dept. oflmfuunology
Harvard Medical School, Boston. MA.-
1998·2005: R~~ident, North'Nester.~ University Feinberg School of Medicine, of
Plastic Surgery, Chicago, IL · ·
; _. ·.·-,_·-._·-, ._· ·- , __ -_,__ ·__ -_._-. _. . ___ · · __ -·-- - '-
2001~2002: Postdoctoral Fellow, Division of Plastic and Reconstructive Surgery,
Northwestern University, Chicago, IL
2005-2006: Craniofacial FelloW, University of Pennsylvania arid 'the Children's Hospital
of Philadelphia, Philadelphia, PA
2006-2011: Assistant Profess.o r of Surgery and PediatriCs, The University of Chicago
Medical Center, Chicago, IL 2006-2Q11
2011-ptes.: Associate Professor ofSurgeryand Pediatrics, The University of Chicago
Medical Center, Chicago, IL 2011-pres.
2006-ptes.: Bernard SarnatScholar of Craniofacial Research, The University of Chicago
Medical Center, ChiCago, IL 2006-present
..
Basic Life Support --2004
Advanced Cardiac Life Support- 2000
American Trauma Life Support- 2002
Illi~oisMe~icaiLicehsure . - 2002 (active)
Penns.Ylvania Medical Licensure-2005 (inactive)
AO ASIF Principles of Operative Treatment of Craniomaxillofacial'I'rauma and
Reconstruction -2005
Certified by the American Board Of Plastic Surgery-2007
Maintenance of Certification (MOC-PS) completed, 2010
Medidll Societies
All1erkan Society M Maxillofacial Surgeons
ActiveMember,Arnerican Society of Plastic Surgeons®
American Cleft Palate Association
Plastic Surgery Research Council
Society of Clinical and Translational Science (Institutional Member)
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1986: National Merit'Scholarship
1990: African-American Cultural Center Leader Award
1992: Bristol-Myers Squibb Commonwealth Fund Award
2001: 3M/Wound Healing Foundation Research Recognition Award
2003: National Register's Who's Who, Executives and Professionals
2004: The Kernahan Award, Northwestern University · ·
·..·2005: Best Clinical Paper Award, Midwestern Association of Plastic Surgeons
2005: Research Paper Award, Chicago Society ofPlastic Surgeons · · ·
2006: Maxillofacial Surgeons Foundation (ASMS/ASIF) Research Award
2009: Komedyplast/ ASCFS Craniofacial Research Grant Award ·
2009: Maxillofacial Surgeons Foundation (ASMS/ ASIF) Research Award
Review Sections and Editorships
2005-present: Guest Editor, CleffPalate Craniofacial Journal
2006-pr2sent:Guest Editor, Journal of Pediatric Neuro~urgery
2006-present: Guest Editor, Plastic Surgery Hyperguide
·•·•··· ••··i·.···.·....·.····.,··.··:.· ·..:,: .. :·::·:: ................ ·:·.. ':·: ..: ..:.·:·.,.··.•. ':.·.·.· .....\·.··...·.·•. ·•. • . .··.•.·.··.'··.·:····.:... ·.·:·•.· •.•• · •.·•••. ·.·:.· •.·.•. •.• ·•. ··•••· • •··...•.•.• :.•.· . ::. . . . ·:.·.··.· .•·•. :.,: . .::- . . ·:·. ·.:.·.··.. ,:· ....,: ... ·,--·:···.··:.:··.· . ·.·.. '-"
Or!liifiiial:ion of Scientific M~litirlgs and !:!!rir~rert~~s
2010-to-Chairman, AO I ASIF Basic Principles in Craniomaxillofacial Fixation,
·Chicago, IL (Course to beheld August, 2012)
University and Department Advisory Committees
R!t~~f~f(~l#ftLt]l arid Par:ite+~~~.hiliVersi tj~•&f ChiCago MOdfC~l
1..
Center,2007-preserit ·. ...• •· .
2. Dir~ctor, Laboratory of Craniofacial Biology and Development,
Uniy~rsity of Chicago Medical Center, 2006-present
3. Member, Regenerative Medicine Group, Department ofSllrgery, University of
Chicago Medical Center
.'·:...:- ·.._
· ·:.· · ,,
Crani.• ·. . ·.·.· . . . .. . ·•·
7. Reid, RR and Dumanian,GAD. A minimalist approach to the.care ofthe indwelling
closed suction drain: A prospective analysis of local woundcomplications.
AI1n~ls of pla~tic Sl!FgE!tY 2q0;3,Sl: 57§ 7578 . .•. ·•.·.· . • ·.· · · •·•·. . • ·.·.· · · · •. \ >
8. Reid R~, Dutra J, ConleypB, Ondra SLandDumaniMogford JE.~iu WR. Rei~R. Chiu CP.S~id H. Chen SJ· Harley CB . .Mustoe TA.
Ade~()Yifal human ~elomerase reverse tra~~qiptase dr~rr1atically improves
ischerr1ic woundryealingwithoutgetrimer1tal)mmune response in anaged rabbit
nl.odel. Hum~r1Gene Therapy. 2006; 1((6):651~60. . ..
ep.
(
17. \Bartlett SP,; ~osee JE, Rei~ ~R, Quinn Severe p~oliferative copgenital
te111Poromandibular joint ankylosis: A proposed treatment protqcol utilizing
disf~.~$·~ipn oste()~e~~sis. Jou~~~lg.f Cranio{~fi~lSurgerr·. ~996; 17(3):60~.-1 o.
18. Od4Q*e M. Reid.Rlt'lu M. FewJW. Periorbitalrejuven~H()n and the At~ican
American p~~ient: a surveyappr'oach. g!astic & Rec()nstruttive Stirgery; 2006;
118(4):1011-8. \ .•. .·.· . . •.••. ·. .•. .. / .
19:Reid RR. Roy N. MogfordJE. Zimmerman H. Lee C. Mustoe TA. Reduction of
hypertr9phic sca[yi~ retrovir~ld.Jliveryof.~ ci?minantneg~tive TGF-peta receptor
II.Jourrial of PlastiC, Reconstructive & Aesthetic Surgery: JPRAS. 2007; 60(1):64-72;
discussion 73-4.
20. Seiber JC, Reid RR, Gershman BA, Sonnad SS, Sutton LN, Whitaker LA, Bartlett SP.
Evolution ofoperative techniques forthe treatmeritof single-suture metopic
syn<)stosis. AnnaisofPlastic Surgery 2007; 59(1.): 6-13.
21. Smartt JM, Reid RR, Singh DJ, Bartlett SP. True lambdoid synostosis: Results of long- ·
term surgicc:H and conservative management. Plastic and Reconstructive Surgery
2007; 120(4): 993-1003.
22 ..BakerS~, ReidRR, B~rkey B, Bartlett SP. Rapid maxillary distraCtion protocol
utilizingthe halo distraction System and rigid internal fixation. Cleft Palate
CraniofacialJournal2007; 44(S): 476-481. · ·
23. Reid RR, Lee MJ, Lewis VL. Postauricular artery island flap for subtotal ear
reconstruction: expanding flap versatility based onzones of regional perfusion.
Plas~. R~constr. ?urg.2008; 1~~(4): 213e-2l4~. ·. ··. ·. ·. ·.. . . ....... i.
24. Derig ZL; Sharff KA, Tang N, Song WX, Luo J, Llio X, Chen J, BennettE, Reid R,
Manning D, XueA, Montag AG, Luu HH, Haydon RC,He TC. Regulation of osteogenic
differentiation during skeletal development. Frontiers in Bioscience 2008; 13:
2001-2021; '
25. Sel~er L Reid R~,C~ike-Obi %S~tton LN,Zac~ai EH, M~Donald-McGin~p, Sonnad
SS, Whitaker LA, Bartlett SP. The changing epidemiologic spectrum of single-suture
synostoses. Plast. Reconstr. Surg. 2008; 122(2): 527-533.
26.. Luo X, Chen J, Song WX, Tang N, Luo J, Deng ZL, Sharff KA, He G, Bi Y, He BC; Bennett
E, Huang J, Kang Q, Jiang W, Su Y, ZhuGH, Yin H, HeY, Wang Y, Souris JS, Cheri L, Zuo
GW, Montag AG, Rei~R, Haydon RC, Luu HH, He TC. Osteogenic BMPs promote
tumor growth of human osteosarcomas that harbor differentiation defects.
Laboratory Investigation 2008; 88(12): 1264-1277.
27. Tang N, Song W-X, Luo J,Luo X, Chen J,Shadf KA, BiY, He BC, Huang JY, Zhu GH, Su
YXi Jiang W, Tang M, HeY, Wang Y, Chen L, Zuo GW, Shen J, Pan X, Reid RR, Luu HH,
HaYciohRC, He tc BMP9-induced osteogenkdifferentiationof mesenchymal
progenitors requires functional canonical Wnt/b-catenin signaling. Journal of
Cellular and Molecular Medicine 2009; l3(8B): 2448-2464.
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28.. {\ganval S1 GupfaA, Grevious MA, Reid ~ll.·Jhe use ofResorbableillipla~ts f()t •·
Mandibular Fixation: A Systematic Review. J. Craniofacial Surg. 2009; 20(2): 331-
339. .\ . .·... . . . i. < >.. .. .. . ••.•
29.·. K::mgQ, Sqrlg'A'·)(•. Luo .Q,TangN, LuoJ, . L~.pX, CryenJ, Bi Y,~~ . B~C,ParK.JKdian~W,
TangY,Huang J,SuY, Zhu G-H, HeY, Yin H,Hu Z, WangY,Ch~n L, Zu()G, Pan XiShen
J,Voke~T, Reid~R, Haydon RC, Luu HH#,and He.J·C#: Acompreh)nsive ana.lysis
?fJhe d~atr91e~8f~M~sinregulfti9g . a.ciiPp~eniC .a9A ost.epgef1ic ciiffeF).ntia.t ion.o f
mesencl1ymal progenitorcells. Stem Cells.a nd Dev~lopmenl2009; 1_~(4): 54§-559.
30. Sharffl5A, Song .'A7·X, Lu?X, Tangf\J, Luo J,Shen J, BiY, He BC, HuangJ, Li X, JiapgW,
zp~ ..F~''•.~~.X·. .I-I~X~ srrnJ,'A'a.I1gY,ch~nL,z. uoq'A', ·. Lil1 ~~.~a.n . x..Jl.ei~ .~Jl.c LPH · n~~
Haydor1RC, HeTC. Hey1Basic H~Hx- LoowHeiix(b~LH) Pr?tein Plays an Important
Role in Mediating BMP9Induced Osteogenic Differentiation of Mesenchymal
Pr?~erlitorCell~.Jo~rnai.?f Biologicfl Chetnistry 20.09; .284(1): .649-~59.
31. ChenE~, Reid ~R, Chike-Obi C; Minugh•Purvis N, 'A7hitakeriLA, Puchala J, Bartlett
SP. Tongue dysmorphology in craniofacial microsomia. Plastic & Reconstructive
Surgery2009; 1-24(2): 583-589. .• . . . ··•····• • . \ ·
32. SeitziA,Adler N,Qdessey E,Reid RR, GottliebLJ. Latissimus dorsi/rib intercostal
myo-osseocutaneo'u s free flap reconstruction in composite defects of the scalp: case
series a9d review oftheliterature. Journal of Reconstructive Microsurgery. 2009;
25(9): 559~567. . .· . <.. > . . · ·.'·. < •• .. •••••· > .
33, Kwal1 D, Reid RR. Regarding "Application-specific selection ofbiomaterials for
pediatric .~raniofacial rec?nstruction: devrloping arationalapproachto guide
clinicalyse." .Plastic &Reconstructive Surgery~ 2009;124(2):.660·661.
34.iRastegar F, Shenaq D, Huang J, Zhang W, Zhang BQ,HeBC; Chen L, Z~o Ciw,Luo Q;
Shi Q, 'A7agner E~., HuangE, Gao Y, Gao JL, Kim SH, Zhou JZ, Bi Y, Su Y, Zhu G, Luo J,
Lt1qX, (lin J,Reid Jl.R, Luu HH, Haydon RC,HeTC.Meser1chylllal stem cells:
Molecular characteristics and clinical applications. World Journal of Stem Cells.
2010; 2(4): 67-80.
35. ShenaqDS,Rastegar F, Petko vic D, Zhang BQ,HeBC,Che9 L, zl1o G'A7, L~oQ, Shi Q,
Wagner ER, Huang E, GaoY, Gao JL, Kim SH, Yang K, Bi Y, SuY, Zhu G, Luo J, Lpo X,
Qin J, Reid RR, Luu HH, Haydon RC and He TC: Mesenchymal Progenitor Cells and
Thei[Ortp?pedic.{\pplica.tions: Forging a Path towards Clinical Trials. Stem Cells
International2010; 519028.
36. Chen L, Jiang W, Huang h He BC, Zuo GW, Zhang W, Luo Q, Shi Q, Zhang BQ, Wagner
ER, LpoJ,TangM,WeitpoltC, Luo X, BiY, SuY, LiuB, Kim SH, He CJ,Hu Y, Shen J,
Rastegar F, Huang E, GaoY, Gao JL, Zhou JZ, Reid RR, Luu HH, HaydonRC, He.JC'
Deng ZL. Insulin-like Growth Factor (IGF2) potentiates BMP9-induced osteogenic
d.i fferenti.a. . tio.·. n ofmese.nch. ymal stem ce·l·. ls a.n d bone fo··r·mation. .·. .·Journal. of Bone · ·a.. n.d·
MirieralResearch 2010; 25(11):. 2447-2459.. . •..•• •.•· •··.•••··• . . <<
37. Wagner ER, Zhu G, Zhang BQ, Luo Q, Shi Q, Huang E, Gao Y, Gao JL, Kim SH, Rastegar
F, Zuo GW, Bi Y, Luo J, Luo X, Huang J, Deng ZL, Reid RR, Luu HH, Haydon RC, He TC.
Therapeutic potential of theWntsignaling pathway in bone metabolic disorders.
Current Moiecular Pharmacology 2011; 4(1): 14-25.
38. Smartt Jr. JS, Elliott R, Re.i d RR, Bartlett SP .. Analysis of thedifferences in the cranial
base and facial skeleton of patients with lambdoid synostosis and defo rmational
plagiocephaly. Plastic and Reconstructive Surgery 2011; 127(1): 303·312.
39. Lee JC*, SpiguelLS*, Shenaq DS, Zhong M, WietholtC, He TC, Reid RR. The role of
RANK·RANKL-OPG axis in cranial suture homeostasis. Journal ofCraniofacial
Surgery 2011; (in ptess--*both authors contributed equally to this work).
Case ID: 110503459
Control No.: 13041685
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Russell R. Reid, MD PhD 7
40. Luther G, Wagner ER, Zhu G, Kang Q, Luo Q, Lamplot J, Bi Y, Luo X, Luo J, Teven C, Shi
Q, Kim SH, Gao JL, Huang E, Yang K, Rames R, Liu X, Li M, Hu N, Liu H, Su Y, Chen L,
He BC, Zuo GW, Deng ZL, Reid RR, Luu HH, Haydon, RC and He TC: (2011) BMP-9
Induced Osteogenic Differentiation of Mesenchymal Stem Cells: Molecular
Mechanism and Therapeutic Potential Current Gene Therapy [in press]
Submitted Manuscripts and Manuscripts in Preparation.
1. Stephanie H Kim, Guowei Zuo, Bai-Cheng He, Ning Hu, Yang Bi, Jinyong Luo, Qing
jo, Lan Zhou, luang, Ke Yang, Jian-L
lunjiang He, Jong Kyung Park, Jiayi Huang, Gai Zhu, Yuxi Su, Xing Liu,
Linyuan Wang, Hong Liu, Liang Chen, Qiong Shi, Quan Kang, Zhong-Liang Deng,
Regulates Bone Mineral Density and Glucose Metabolism, (submitted).
2. Qiong Shi, Yaguqng, Jinyong Luo, Gaohui Zhu, Liang Chen, Bai-Cheng He, Guo-Wei
Zuo, Jiayi Huang, Qing Luo, Stephanie H. Kim, Enyi Huang, Jian-Li Gao, Ke Yang,
ag Zhang,
Chuan He: Cysteine-rich with EGF-like domains 2 (CRELD2) Plays an Important
Role in BMP9-induced Osteogenic Differentiation of Mesenchymal Stem Cells and
Bone Formation, (submitted).
3. Liang Chen, Wei Jiang, Bai-Cheng He, Guo-Wei Zuo, Qing Luo, Bing-Qiang Zhang,
Christian Wietholt, Qiong Shi, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H.
Kim, Ke Yang, Eric R. Wagner, Jinyong Luo, Xiaoji Luo, Yang Bi, Yuxi Su, Bo Liu,
Jikun Shen, Xing Liu, Ning Hu, Mi Li, Linyuan Wang, Russell R. Reid, Hue H. Luu,
Zhong-Liang Deng, Tong-Chuan He* and Rex C. Haydon* Insulin-like Growth
Factor-1 (IGF1) acts synergistically with Bone Morphogenetic Protein-9 (BMP9)
during osteogenesis. Molecular Therapy (in preparation) (*co-corresponding
authors
Invited Reviews.
Reid RR. Facial growth and timing of surgical intervention. Clinics in Plastic Surgery. 2007;
34(3): 357-367.
Book Chapters.
1. Reid RR. Lip Reconstruction. Chapter in Plastic and Reconstructive Surgery: Board
Review. Lin S. and Hijjawi J., eds. McGraw-Hill, Inc. 2005.
2. Percec I, Reid RR, Bartlett SP. Distraction of the Craniofacial Skeleton: Experience
at the University of Pennsylvania. Chapter in Liu C, ed. Distraction Osteogenesis of
the Craniomaxillofacial Skeleton. The People’s Hygiene Publisher, Beijing, China.
2005.
3. Reid RR. Head and Neck. Chapter 4 in Essentials for Students. American Society of
Plastic Surgeons/Plastic Surgery Educational Foundation, 7th ed. (2007).
4. Reid RR. Skin and Subcutaneous Lesions. Chapter 3 in Essentials for Students.
American Society of Plastic Surgeons/Plastic Surgery Educational Foundation, 7th
ed. (2007).
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Russell R. Reid, MD PhD 8
5. Reid RR, Lu L, Dumanian GA. Pediatric pressure sores. Chapter 59 in Bentz ML,
Bauer BS, Zuker RM, ed. Principles and Practice of Pediatric Plastic Surgery, Quality
Med. Publishing, Inc.; St. Louis, 2008.
6. Gottlieb LJ, Reid RR. Multi-Staged Autologous Reconstruction of the Face. Book
Chapter in Semionow, M, ed. The Know-How of Facial Transplantation, in press.
7. Lee JC, Reid RR, Gottlieb LJ. Pediatric Trunk Defects. Book Chapter in Neligan P., ed.
Plastic Surgery 2011,3rd ed., in press.
8. Seitz IA, Teven CM, Reid RR. Repair and Grafting of Bone. Book Chapter in Neligan P.
ed. Plastic Surgery 2011,3rd ed., in press.
Scientific Papers and Scientific Exhibits
Shenaq D, Teven C, He TC, Reid R. The osteogenic characteristics of immortalized calvarial
cells. Oral presentation at the 3rd European Plastic Surgery Research Council (Hamburg,
Germany), 2011.
Spiguel LR, Lee J, Sheine Y, He TC, and Reid RR.
Osteoimmunology and cranial suture biology. Oral presentation at the 54th Plastic
Surgery Research Council (Pittsburgh, PA) and Poster presentation at the 16th Annual
Charles B. Huggins Research Council, University of Chicago (Chicago, IL), 2009.
Seitz 1A, Spiguel LR, Teven CM, Wietholt C, Januszek M, Haydon RC, Luu HH, He TC, Reid RR.
The differential effects of BMP-2 and BMP-9 in critical-sized, murine cranial defects.
Oral presentation at the XHIth Congress of the International Society of Craniofacial
Surgeons, Oxford, UK and Poster presentation at the 16th Annual Charles B. Huggins
Research Council, University of Chicago (Chicago, IL) 2009.
Teven CM, Su Y, Bi Y et al. (Reid RR senior author). A novel delivery system of pulsed
electromagnetic fields accelerates osteogenic differentiation of mesenchymal stem
cells. Oral presentation at the 54th Plastic Surgery Research Council (Pittsburgh, PA) and
Poster presentation at the 16th Annual Charles B. Huggins Research Symposium, University
of Chicago (Chicago, IL), 2009.
Mou S, Sharff K, Song WX, He TC, Reid RR. Enhanced osteogenic capacity of bone
precursor cells co-transduced with human telomerase and bone morphogenetic
protein 9. Oral presentation at the 53rd Plastic Surgery Research Council (Springfield, IL)
and Poster presentation at the 15th Annual Charles B. Huggins Research Symposium,
Department of Surgery, University of Chicago, Chicago, IL 2008.
Reid RR, Selber J, Chike-Obi C, Bartlett SP. Demographic Shift in the Non-syndromic
Craniosynostoses. Scientific paper presented at the 1st Annual Whitaker Lectureship,
University of Pennsylvania, Philadelphia, PA 2006.
Smartt JM, Reid RR, Singh DJ, Bartlett SP. True Lambdoid Craniosynostosis: Results of
Surgical Therapy. Scientific paper presented at the XI International Society for Craniofacial
Surgeons Biennial Meeting, Queensland, Australia, 2005.
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Russell R. Reid, MD PhD 9
Reid RR, Margulis A, Patel PK. Resorbable versus Titanium Fixation of Le Fort I
Osteotomies in the Cleft Population. Scientific paper presented at the Midwestern
Association of Plastic Surgeons Meeting, Chicago, IL, 2005 (Best Clinical Paper Award)
Reid RR, Roy N, Mogford JE, Zimmerman H, Lee C, Mustoe TA. Retroviral Delivery of a
Dominant Negative TGF Beta Receptor II Mitigates Scar in A Rabbit Model of Scar
Hypertrophy. Research paper award, Chicago Society of Plastic Surgeons - 2005. Scientific
paper presented at the Wound Healing Society Meeting, Atlanta, GA, 2004.
Reid RR, Bauer BS, Fine NA. The Role of "Double Delay” of Expanded Flaps in Pediatric
Reconstruction. Scientific paper presented at the Midwestern Association of Plastic
Surgeons Meeting, Chicago, IL, 2004.
Reid RR, Said HK, Haines 111 GK, Few JW. The Upper Eyelid: The Introduction of the Septal
Extension. Scientific paper presented at the Midwestern Association of Plastic Surgeons
Meeting, Chicago, IL, 2004.
Reid RR, Dumanian GA. Panniculectomy andThe Separation of Parts Hernia Repair: A
Solution for the Large Infraumbilical Hernia in the Obese Patient. Scientific paper presented
at the Midwestern Association of Plastic Surgeons Meeting, Chicago, IL, 2004.
Reid RR, Greve SD, Casas LA. The Effect of Zafirlukast (Accolate) on Early Capsular
Contracture in the Primary Augmentation Patient: A Pilot Study. Poster presented at the
American Society of Plastic Surgery, San Diego, CA, 2003.
Reid RR, Said HK and Few, JW. The Upper Eyelid: Relevant Septal Anatomy in Aesthetic
Surgery. Scientific paper presented (by JWF) at the American Society of Aesthetic Plastic
Surgery, Boston, MA, 2003.
Reid RR, Said HK, Mogford JE and Mustoe TA. The Future of Wound Healing: Surgical
Models in Transgenic Mice. Scientific paper presented at the American College of Surgeons,
San Francisco, CA, 2002.
Reid RR, Mogford JE, Zhang M, Wakim, B., Carroll MC, Mustoe TA. The Binding of Natural
IgM to Hypoxic Endothelium: Implications in Ischemia-Reperfusion Injury. Poster presented
at The Wound Healing Society, Baltimore, MD, 2002
Reid RR, Shohet JS, Pemberton PA, Carroll, MC: Localization of C3-IgG covalent binding site.
Poster presented at Federation of American Societies for Experimental Biology, Anaheim,
CA., 1994
Reid RR, Shohet JS, Pemberton PA, Carroll, MC: Localization of C3-IgG covalent binding site.
Scientific paper presented at XVth International Complement Workshop. Kyoto. Japan. 1993
Invited Visiting Professorships/Lectures/Grand Rounds
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'. ■;:S CivilAdministration- 1
ir- ::
N. ESSOUNNI Russell R. Reid, MD PhD
0
Co-Chair, Basic Craniomaxillofacial Principles Course, AO North America, Chicago, IL,
2012.
Invited Faculty, American Society of Plastic Surgeons Oral and Written Board
Preparation Course. "Implants and Biomaterials.'’ Chicago, IL, 2011.
Advances in Pediatrics 2011 Symposium. Advocate Lutheran General Hospital/Advocate
Lutheran General Children’s Hospital Cleft Lip and Palate, Park Ridge, IL, March 11,2011.
Grand Rounds, Section of Pediatric Surgery, University of Chicago Medical Center.
Wound Healing, Chicago, IL, November 9, 2010.
Session Co-Chair, Research, Plastic Surgery 2010, American Society of Plastic
Surgeons, Toronto, ON, Canada, October 4, 2010.
Session Co-Chair, Craniofacial Research, 2nd European Plastic Surgery Research
Council, Hamburg, Germany, August 28, 2010.
Session Co-Chair, Craniofacial Biology 2. 67th Annual Meeting, American Cleft Palate-
Craniofacial Association, Dallas, TX, March 19, 2010.
Grand Rounds, Department of Pediatrics, University of Chicago Medical Center. The
Nonsyndromic Craniosynostoses. Chicago, IL, March 12, 2009.
Grand Rounds, Section of Neurosurgery, University of Chicago Medical Center. The
Syndromic Craniosynostoses. Chicago, IL, January 7, 2009.
Reid RR. Mandibular Fractures. National Medical Association: 2008 Annual Convention &
Scientific Assembly, Atlanta, GA, July 28, 2008.
Reid RR. Mandibular Distraction Osteogenesis. National Medical Association: 2008 Annual
Convention & Scientific Assembly, Atlanta, GA, July 28, 2008.
Smartt JM, Reid RR, Singh DJ, Bartlett SP. Lambdoid Craniosynostosis vs. Positional
Plagiocephaly: Diagnosis and Treatment Options. Panel Session: Interdisciplinary
Problem-Solving in Pediatric Neurosurgery and Craniomaxillofacial Surgery
(ImproMed) (presented by SP Bartlett), Phoenix, AZ, 2008.
Grand Rounds, Department of Pediatrics, Advocate Lutheran General Hospital. The
Syndromic Craniosynostoses. Park Ridge, IL, December 18, 2007.
Grand Rounds, Midland Memorial Hospital. Abdominal Wall Reconstruction, Midland
TX. May 16, 2007.
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■ mi Si
I Russell R. Reid, MD PhD 1
1
Moderator, Faculty Session. 14th Annual Charles B. Huggins Research Symposium,
University of Chicago, Department of Surgery, May 5, 2007.
Grand Rounds, Department of Pediatrics, University of Chicago. The Syndromic
Craniosynostoses: Reconstructive Approaches. January 18, 2007.
Instructor, ASMS BASIC MAXILLOFACIAL PRINCIPLES & TECHNIQUES.
Chicago, IL August, 2006.
Controversies in Pediatric Craniofacial Trauma. Synthes CMF Intermediate Training
Curriculum, Paoli, PA 2005, 2006.
Craniosynostosis. Synthes CMF Intermediate Curriculum, Paoli, PA 2005, 2006.
Distraction Osteogenesis. Synthes CMF Intermediate Curriculum, Paoli, PA 2005, 2006.
Positional Plagiocephaly versus True Lambdoid Synostosis. Grand Rounds, Brown
University Division of Plastic Surgery, 2005.
Positional Plagiocephaly versus True Lambdoid Synostosis. Grand Rounds, University
of Chicago Section of Plastic Surgery, 2005.
Sponsored Scholarly Activities
ADA Carol Kuckein Grant, 2011. Proposal Title: "The Use of a Novel, Three-Dimensional
Biocompatible Scaffold to Deliver Osteoprogenitor Cells to a Critical-Sized Calvarial Defect.”
Awardee: Mr. Chad M. Teven, MSIV, Pritzker School of Medicine. PI: Russell R. Reid
AOA Carol Kuckein Grant, 2010. "Proposal Title: The Differential Effects of Cellularly
Engineered BMP-2, BMP-9 and RunX2 on Bone Healing in Murine Critical-Sized Calvarial
Defects." Awardee: Ms. Deana Shenaq, MSIV, Pritzker School of Medicine. PI: Russell R. Reid
"The Role of RANK/RANKL/OPG Axis in Cranial Suture Homeostasis." Oral
Presentation: Dr. Justine Lee, Resident, Plastic Surgery, Univ. of Chicago. PI:
Russell R. Reid. Plastic Surgery 2010, Toronto ON, Canada, October 2010 and 3rd
International Conference on Osteoimmunology, Interactions of the Immune and
Skeletal Systems. Santorini, Greece, June 2010.
Research Support-
Current Support.
P.I. Reid RR. NIH/NIDCR K08 Clinical Investigator Award/Mentored Research Award
1-K08DE020140-01 (9/1/2009-8/31/2014): Differential Effects of BMPs on Healing of
Craniofacial Defects. ($123,550 per annum; project period 5 years).
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w aaamt
P.I. Reid RR. Plastic Surgery Education Foundation (PSEF) Seed Grant (7/1/2010-
6/30/2011) Principal Investigator: The Role of RANK/RANKL/OPG Axis in Cranial Suture
Homeostasis ($10,000).
Past Support.
P.I. Reid RR. 3M Wound Healing Research Award (2001)
The Role of Natural Antibodies in Ischemia-Reperfusion Injury ($5,000).
P.I. Few Jr., JW. Co-P.I. Reid RR. Wound Healing Research Grant, Besin International
Ltd. (2003) Co-Investigator ($250,000+).
P.I. Reid RR. Children's Memorial Research Foundation, Inc. (2004)
Genetic Expression of the Developing Murine Auricle: Implications in Congenital Ear
Deformities ($3,600).
P.I. Reid RR. Maxillofacial Surgeons Foundation of the American Society of
Maxillofacial Surgeons Research Award (2006)
Acceleration of Mandibular Distraction-Associated Bony Regenerate Healing by Electrical
Field Stimulation ($3,750).
P.I. Reid RR. Plastic Surgery Education Foundation (PSEF) Basic Research Grant
(2008). Differential Effects of Human Telomerase and Bone Morphogenetic Proteins on
Bone Healing in Murine Models. ($ 5,000 #BRG48-08).
P.I. Reid RR. Advocate Lutheran General Hospital Partners Endowment (2008).
Principal Investigator: The Development and Implementation of a Computerized
Craniofacial Database ($15,000).
P.I. Reid RR. Komedyplast/American Society of Craniofacial Surgeons Craniofacial
Research Grant Award (2009). Osteoimmunology and Suture Biology. ($5,000).
P.I. Reid RR. Maxillofacial Surgeons Foundation of the American Society of
Maxillofacial Surgeons Research Award (2009)
The Use of Pulsed Electromagnetic Fields for the Enhancement of the Consolidation Period
of Distraction Osteogenesis ($3,000).
Mentoring and Supervision of Medical Students.
Name: Shanshan Mou, M.D., M.S.
Duration: June 2007 - August 2007
Research Project: Enhanced Osteogenic Capacity of Bone Precursor Cells Co-transduced
with Human Telomerase and Bone Morphogenetic Protein 9.
Awards/Distinctions: Recipient of 2007 Summer Research Program of Pritzker School of
Medicine; Recipient of the Basic Science Excellence Award, 2007 Summer Research
Preview
FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 EXHIBIT E FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 SUPREME COURT OF THE STATE OF NEW YORK COUNTY OF SUFFOLK Index Number: 26910/12 xxxxxx xxxxxxxx, on behalf of C S , an infant under the age of 18, and xxxxxx xxxxxxxx, PLAINTIFF’S EXPERT Individually, WITNESS EXCHANGE CRANIOFACIAL Plaintiffs, RECONSTRUCTIVE & PLASTIC SURGERY -against- RONALD J. TADEO, M.D., RICHARD PITCH, M.D., SCOTT BERLIN, M.D., SHORE PSYCHIATRIC CENTER, FAMILY PSYCHOLOGY OF LONG ISLAND, BERLIN OBGYN ASSOCIATES, JANSSEN PHARMACEUTICALS, INC. and ZYDUS PHARMACEUTICALS (USA), INC., Defendants. Plaintiffs, by their attorneys, NAPOLI SHKOLNIK PLLC, as and for an Expert Witness Disclosure pursuant to CPLR §3101(d), reserves the right to call the following witness at the time of trial: Russell R. Reid, M.D., Ph.D. The University of Chicago Medical Center 5841 S. Maryland Avenue Chicago, IL 60637 1. Annexed hereto is the curriculum vitae of Russell R. Reid, M.D., Ph.D. which sets out his qualifications, educational background, training, membership in societies, academic appointments and committees and publication and teaching experience. 2. In particular, Dr. Reid is an experienced craniofacial plastic and reconstructive surgeon who is licensed to practice medicine in the state of Illinois. He is board certified by the American Board of Plastic Surgery. He received his medical degree Northwestern University in FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 1998, where he also earned a Ph.D. in Pathology. He completed his residency and fellowship in Plastic Surgery at the University of Chicago/McGraw Medical Center in 2005. He completed a fellowship in craniofacial surgery at the University of Pennsylvania in 2006. 3. Dr. Reid specializes in the field of pediatric craniofacial reconstructive and plastic surgery. He is a Director of the Cleft Lip and Palate Team and Director of the Laboratory and Director of the Craniofacial Anomalies Multidisciplinary Program both with the University of Chicago Medical Center, where he also serves as a Professor of Surgery and Pediatrics. 4. Dr. Reid is expected to opine at the time of trial, on behalf of infant plaintiff, C S , with regard to the permanent disability of plaintiff, as a result of teratogenic injuries he sustained in utero from Topamax/topiramate, which resulted in a bilateral cleft lip and palate, developmental delays, hearing delays, and severe mental anguish and distress. More particularly, Dr. Reid is expected to testify pertaining to the plaintiff’s physical, ailments, personal injuries with respect to their implications on C craniofacial growth and development, and his need for future treatment including surgery, and how they are all sequelae of the cleft lip and cleft palate C developed in utero. 5. Dr. Reid will opine that due to the subject malpractice, plaintiff, C S , has suffered serious, permanent and debilitating personal injuries, which adversely affect plaintiff’s past, present and future health status and mental health status, which will continue into adulthood and negatively affect quality of life. 6. Dr. Reid will opine in regards to the medical diagnoses and conclusions, relevant to the plaintiff’s health status, as a result of the injuries in utero he sustained which are the subject of this lawsuit. 7. Dr. Reid is expected to opine on how craniofacial defects begin in embryonic FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 development. He will testify on how the fetal palate, lips, nose, and jaw develop in the first few weeks of pregnancy, and the effects of teratogens, including Topamax/topiramate, on said development. It is Dr. Reid’s opinion that Topamax/topiramate has the ability to significantly alter the activity of important cell signaling molecules (proteins), which can be translated to the context of the developing embryo. 8. Dr. Reis is expected to opine that C craniofacial malformations, specifically cleft lip palate consistent with· abnormal craniofacial development due to perturbations of select signaling.· pathways during embryogenesis, and that development of the craniofacies requires strict coordination of cellular activity, which is controlled by cell-signaling proteins to regulate cellular communication. He will opine that Topiramate ultimately impairs embryonic cellular differentiation and growth as it is shown to interfere and disrupt these proteins and that such a disruption can lead to the induction of congenital defects. 9. Dr. Reid will opine that craniofacial defects are among the known congenital malformations occurring at a higher prevalence in children exposed to maternal use of topiramate. Oral clefts, particularly cleft lip and. palate, are craniofacial defects known to ·occur due to alteration of the activity of signaling proteins. 10. Dr. Reid will opine that C cleft lip and palate ate consistent with the congenital malformations seen in children born to mothers who ingested Topamax/topiramate during pregnancy. This is supported by the facts that C mother ingested this medication during the first trimester and the lack of other statistically significant comorbidities. 11. Dr. Reid’s opinion is based on his extensive education, knowledge of and expertise in plastic and reconstructive craniofacial surgery, his experience treating children with cleft lips and palates, his academic research on the subject, all medical records relevant in this FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 matter, all pleadings and documents exchanged in this matter, as well as deposition testimony. 12. Dr. Reid will opine that C S will continue to have permanent deficits that will require medical treatment and procedures for the foreseeable future. 13. Dr. Reid will opine that Topamax/topiramate is causally associated with oral clefts in infants born to mothers who ingest this medication during the first trimester and in particular that C S injuries are of a direct causal relationship the subject malpractice. 14. Dr. Reid will also rebut defendants’ medical expert’s testimony and will comment on any and all evidence and exhibits used at the time of trial. 15. Plaintiff reserves his right to submit additional expert information when and if it becomes available to plaintiffs and their counsel, including a supplemental report. Dated: Melville, New York July 12, 2022 Yours, etc. ___________________________ xxxxxx xxxxxxx NAPOLI SHKOLNIK PLLC Attorneys for Plaintiff 400 Broadhollow Road, Suite 305 Melville, NY 11747 (212) 397-1000 To: MARTIN CLEARWATER & BELL LLP Attorneys for Defendants RONALD J. TADEO, M.D. and SHORE PSYCHIATRIC CENTER 90 Merrick Ave, Suite 401 East Meadow, NY 11554 516-222-8500 FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 CURRICULUM VITAE RusseiiRbger Reid, MtJ PhD Associate Professor of Surgery · Bernard Sarnat Scholar of Craniofacial Research Director~ Cleft Lip and Palate Team . · ·.· . ·Department of Surgery/Section of Plastic and Reconstructive Surgery The University of Chicago Medical Center · .·. .·· · 5841 South Maryland Avenue, M/C 6035, Chicago, IL 60637 Tel.: (773)-702~6302 · · · . (773)~ 702-8985 Facsimile: (773)-702-1634 . Email: rreid@surgery:bsd.uchicago.edu Assistant ~r()f~ssor of. Pediatrics, 1he University of Chicago ~edical Center Attending Surgeon, Advocate Lutheran General Childreri'sHospital M:Tbe~, pepa~~ment~f Surg~ry qu~lity Subcom~ittee (University of Chi~ago) Member,' Edl1catiop Cortill1ittee,American Society of Maxillofacial Surgeons Member, Research Committee, American Society ofAesthetic Plastic Surgeons Invited Reviewer, Cleft Palate Craniofacial journal · Invited Reviewer,journalof Pediatric Neurosurgery · Education Institution and Field B.A. Yale lJnivet~ity, NewHiven, ConnectiCut Bachelor of Arts in Literature (Magna Cum Laude) Distinction in the Major, May, 1990 M.D. Harvard Medieal School, Boston, MA, June,1998 Ph.D, Harvard Medical School, Boston, MA Department of Pathology(Iminunology), advisor: ~ichae.rc. Carroll, Pp.D. ancl the late Fred s. Rosen, M.D., June,1998 Internship /Residency Int:~ratecl Prog~~m in Plastic Surgery Northwestern UniversityjMcGaw Medical Center Chicago, IL (1998-2005) Chairman: Thomas A. Mustoe, M.D. F.A.C.S. Fellowship Craniofacial Fellow, University of Pennsylvania Philadelphia, PA (2005-2006) Program Director: Scott P. Bartlett, M.D. F.A.C.S FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 Training and Employment 1992-1996: Predpetoral FeHlo\JV,Dept. oflmfuunology Harvard Medical School, Boston. MA.- 1998·2005: R~~ident, North'Nester.~ University Feinberg School of Medicine, of Plastic Surgery, Chicago, IL · · ; _. ·.·-,_·-._·-, ._· ·- , __ -_,__ ·__ -_._-. _. . ___ · · __ -·-- - '- 2001~2002: Postdoctoral Fellow, Division of Plastic and Reconstructive Surgery, Northwestern University, Chicago, IL 2005-2006: Craniofacial FelloW, University of Pennsylvania arid 'the Children's Hospital of Philadelphia, Philadelphia, PA 2006-2011: Assistant Profess.o r of Surgery and PediatriCs, The University of Chicago Medical Center, Chicago, IL 2006-2Q11 2011-ptes.: Associate Professor ofSurgeryand Pediatrics, The University of Chicago Medical Center, Chicago, IL 2011-pres. 2006-ptes.: Bernard SarnatScholar of Craniofacial Research, The University of Chicago Medical Center, ChiCago, IL 2006-present .. Basic Life Support --2004 Advanced Cardiac Life Support- 2000 American Trauma Life Support- 2002 Illi~oisMe~icaiLicehsure . - 2002 (active) Penns.Ylvania Medical Licensure-2005 (inactive) AO ASIF Principles of Operative Treatment of Craniomaxillofacial'I'rauma and Reconstruction -2005 Certified by the American Board Of Plastic Surgery-2007 Maintenance of Certification (MOC-PS) completed, 2010 Medidll Societies All1erkan Society M Maxillofacial Surgeons ActiveMember,Arnerican Society of Plastic Surgeons® American Cleft Palate Association Plastic Surgery Research Council Society of Clinical and Translational Science (Institutional Member) FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 1986: National Merit'Scholarship 1990: African-American Cultural Center Leader Award 1992: Bristol-Myers Squibb Commonwealth Fund Award 2001: 3M/Wound Healing Foundation Research Recognition Award 2003: National Register's Who's Who, Executives and Professionals 2004: The Kernahan Award, Northwestern University · · ·..·2005: Best Clinical Paper Award, Midwestern Association of Plastic Surgeons 2005: Research Paper Award, Chicago Society ofPlastic Surgeons · · · 2006: Maxillofacial Surgeons Foundation (ASMS/ASIF) Research Award 2009: Komedyplast/ ASCFS Craniofacial Research Grant Award · 2009: Maxillofacial Surgeons Foundation (ASMS/ ASIF) Research Award Review Sections and Editorships 2005-present: Guest Editor, CleffPalate Craniofacial Journal 2006-pr2sent:Guest Editor, Journal of Pediatric Neuro~urgery 2006-present: Guest Editor, Plastic Surgery Hyperguide ·•·•··· ••··i·.···.·....·.····.,··.··:.· ·..:,: .. :·::·:: ................ ·:·.. ':·: ..: ..:.·:·.,.··.•. ':.·.·.· .....\·.··...·.·•. ·•. • . .··.•.·.··.'··.·:····.:... ·.·:·•.· •.•• · •.·•••. ·.·:.· •.·.•. •.• ·•. ··•••· • •··...•.•.• :.•.· . ::. . . . ·:.·.··.· .•·•. :.,: . .::- . . ·:·. ·.:.·.··.. ,:· ....,: ... ·,--·:···.··:.:··.· . ·.·.. '-" Or!liifiiial:ion of Scientific M~litirlgs and !:!!rir~rert~~s 2010-to-Chairman, AO I ASIF Basic Principles in Craniomaxillofacial Fixation, ·Chicago, IL (Course to beheld August, 2012) University and Department Advisory Committees R!t~~f~f(~l#ftLt]l arid Par:ite+~~~.hiliVersi tj~•&f ChiCago MOdfC~l 1.. Center,2007-preserit ·. ...• •· . 2. Dir~ctor, Laboratory of Craniofacial Biology and Development, Uniy~rsity of Chicago Medical Center, 2006-present 3. Member, Regenerative Medicine Group, Department ofSllrgery, University of Chicago Medical Center .'·:...:- ·.._ · ·:.· · ,, Crani.• ·. . ·.·.· . . . .. . ·•· 7. Reid, RR and Dumanian,GAD. A minimalist approach to the.care ofthe indwelling closed suction drain: A prospective analysis of local woundcomplications. AI1n~ls of pla~tic Sl!FgE!tY 2q0;3,Sl: 57§ 7578 . .•. ·•.·.· . • ·.· · · •·•·. . • ·.·.· · · · •. \ > 8. Reid R~, Dutra J, ConleypB, Ondra SLandDumaniMogford JE.~iu WR. Rei~R. Chiu CP.S~id H. Chen SJ· Harley CB . .Mustoe TA. Ade~()Yifal human ~elomerase reverse tra~~qiptase dr~rr1atically improves ischerr1ic woundryealingwithoutgetrimer1tal)mmune response in anaged rabbit nl.odel. Hum~r1Gene Therapy. 2006; 1((6):651~60. . .. ep. ( 17. \Bartlett SP,; ~osee JE, Rei~ ~R, Quinn Severe p~oliferative copgenital te111Poromandibular joint ankylosis: A proposed treatment protqcol utilizing disf~.~$·~ipn oste()~e~~sis. Jou~~~lg.f Cranio{~fi~lSurgerr·. ~996; 17(3):60~.-1 o. 18. Od4Q*e M. Reid.Rlt'lu M. FewJW. Periorbitalrejuven~H()n and the At~ican American p~~ient: a surveyappr'oach. g!astic & Rec()nstruttive Stirgery; 2006; 118(4):1011-8. \ .•. .·.· . . •.••. ·. .•. .. / . 19:Reid RR. Roy N. MogfordJE. Zimmerman H. Lee C. Mustoe TA. Reduction of hypertr9phic sca[yi~ retrovir~ld.Jliveryof.~ ci?minantneg~tive TGF-peta receptor II.Jourrial of PlastiC, Reconstructive & Aesthetic Surgery: JPRAS. 2007; 60(1):64-72; discussion 73-4. 20. Seiber JC, Reid RR, Gershman BA, Sonnad SS, Sutton LN, Whitaker LA, Bartlett SP. Evolution ofoperative techniques forthe treatmeritof single-suture metopic syn<)stosis. AnnaisofPlastic Surgery 2007; 59(1.): 6-13. 21. Smartt JM, Reid RR, Singh DJ, Bartlett SP. True lambdoid synostosis: Results of long- · term surgicc:H and conservative management. Plastic and Reconstructive Surgery 2007; 120(4): 993-1003. 22 ..BakerS~, ReidRR, B~rkey B, Bartlett SP. Rapid maxillary distraCtion protocol utilizingthe halo distraction System and rigid internal fixation. Cleft Palate CraniofacialJournal2007; 44(S): 476-481. · · 23. Reid RR, Lee MJ, Lewis VL. Postauricular artery island flap for subtotal ear reconstruction: expanding flap versatility based onzones of regional perfusion. Plas~. R~constr. ?urg.2008; 1~~(4): 213e-2l4~. ·. ··. ·. ·. ·.. . . ....... i. 24. Derig ZL; Sharff KA, Tang N, Song WX, Luo J, Llio X, Chen J, BennettE, Reid R, Manning D, XueA, Montag AG, Luu HH, Haydon RC,He TC. Regulation of osteogenic differentiation during skeletal development. Frontiers in Bioscience 2008; 13: 2001-2021; ' 25. Sel~er L Reid R~,C~ike-Obi %S~tton LN,Zac~ai EH, M~Donald-McGin~p, Sonnad SS, Whitaker LA, Bartlett SP. The changing epidemiologic spectrum of single-suture synostoses. Plast. Reconstr. Surg. 2008; 122(2): 527-533. 26.. Luo X, Chen J, Song WX, Tang N, Luo J, Deng ZL, Sharff KA, He G, Bi Y, He BC; Bennett E, Huang J, Kang Q, Jiang W, Su Y, ZhuGH, Yin H, HeY, Wang Y, Souris JS, Cheri L, Zuo GW, Montag AG, Rei~R, Haydon RC, Luu HH, He TC. Osteogenic BMPs promote tumor growth of human osteosarcomas that harbor differentiation defects. Laboratory Investigation 2008; 88(12): 1264-1277. 27. Tang N, Song W-X, Luo J,Luo X, Chen J,Shadf KA, BiY, He BC, Huang JY, Zhu GH, Su YXi Jiang W, Tang M, HeY, Wang Y, Chen L, Zuo GW, Shen J, Pan X, Reid RR, Luu HH, HaYciohRC, He tc BMP9-induced osteogenkdifferentiationof mesenchymal progenitors requires functional canonical Wnt/b-catenin signaling. Journal of Cellular and Molecular Medicine 2009; l3(8B): 2448-2464. FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 28.. {\ganval S1 GupfaA, Grevious MA, Reid ~ll.·Jhe use ofResorbableillipla~ts f()t •· Mandibular Fixation: A Systematic Review. J. Craniofacial Surg. 2009; 20(2): 331- 339. .\ . .·... . . . i. < >.. .. .. . ••.• 29.·. K::mgQ, Sqrlg'A'·)(•. Luo .Q,TangN, LuoJ, . L~.pX, CryenJ, Bi Y,~~ . B~C,ParK.JKdian~W, TangY,Huang J,SuY, Zhu G-H, HeY, Yin H,Hu Z, WangY,Ch~n L, Zu()G, Pan XiShen J,Voke~T, Reid~R, Haydon RC, Luu HH#,and He.J·C#: Acompreh)nsive ana.lysis ?fJhe d~atr91e~8f~M~sinregulfti9g . a.ciiPp~eniC .a9A ost.epgef1ic ciiffeF).ntia.t ion.o f mesencl1ymal progenitorcells. Stem Cells.a nd Dev~lopmenl2009; 1_~(4): 54§-559. 30. Sharffl5A, Song .'A7·X, Lu?X, Tangf\J, Luo J,Shen J, BiY, He BC, HuangJ, Li X, JiapgW, zp~ ..F~''•.~~.X·. .I-I~X~ srrnJ,'A'a.I1gY,ch~nL,z. uoq'A', ·. Lil1 ~~.~a.n . x..Jl.ei~ .~Jl.c LPH · n~~ Haydor1RC, HeTC. Hey1Basic H~Hx- LoowHeiix(b~LH) Pr?tein Plays an Important Role in Mediating BMP9Induced Osteogenic Differentiation of Mesenchymal Pr?~erlitorCell~.Jo~rnai.?f Biologicfl Chetnistry 20.09; .284(1): .649-~59. 31. ChenE~, Reid ~R, Chike-Obi C; Minugh•Purvis N, 'A7hitakeriLA, Puchala J, Bartlett SP. Tongue dysmorphology in craniofacial microsomia. Plastic & Reconstructive Surgery2009; 1-24(2): 583-589. .• . . . ··•····• • . \ · 32. SeitziA,Adler N,Qdessey E,Reid RR, GottliebLJ. Latissimus dorsi/rib intercostal myo-osseocutaneo'u s free flap reconstruction in composite defects of the scalp: case series a9d review oftheliterature. Journal of Reconstructive Microsurgery. 2009; 25(9): 559~567. . .· . <.. > . . · ·.'·. < •• .. •••••· > . 33, Kwal1 D, Reid RR. Regarding "Application-specific selection ofbiomaterials for pediatric .~raniofacial rec?nstruction: devrloping arationalapproachto guide clinicalyse." .Plastic &Reconstructive Surgery~ 2009;124(2):.660·661. 34.iRastegar F, Shenaq D, Huang J, Zhang W, Zhang BQ,HeBC; Chen L, Z~o Ciw,Luo Q; Shi Q, 'A7agner E~., HuangE, Gao Y, Gao JL, Kim SH, Zhou JZ, Bi Y, Su Y, Zhu G, Luo J, Lt1qX, (lin J,Reid Jl.R, Luu HH, Haydon RC,HeTC.Meser1chylllal stem cells: Molecular characteristics and clinical applications. World Journal of Stem Cells. 2010; 2(4): 67-80. 35. ShenaqDS,Rastegar F, Petko vic D, Zhang BQ,HeBC,Che9 L, zl1o G'A7, L~oQ, Shi Q, Wagner ER, Huang E, GaoY, Gao JL, Kim SH, Yang K, Bi Y, SuY, Zhu G, Luo J, Lpo X, Qin J, Reid RR, Luu HH, Haydon RC and He TC: Mesenchymal Progenitor Cells and Thei[Ortp?pedic.{\pplica.tions: Forging a Path towards Clinical Trials. Stem Cells International2010; 519028. 36. Chen L, Jiang W, Huang h He BC, Zuo GW, Zhang W, Luo Q, Shi Q, Zhang BQ, Wagner ER, LpoJ,TangM,WeitpoltC, Luo X, BiY, SuY, LiuB, Kim SH, He CJ,Hu Y, Shen J, Rastegar F, Huang E, GaoY, Gao JL, Zhou JZ, Reid RR, Luu HH, HaydonRC, He.JC' Deng ZL. Insulin-like Growth Factor (IGF2) potentiates BMP9-induced osteogenic d.i fferenti.a. . tio.·. n ofmese.nch. ymal stem ce·l·. ls a.n d bone fo··r·mation. .·. .·Journal. of Bone · ·a.. n.d· MirieralResearch 2010; 25(11):. 2447-2459.. . •..•• •.•· •··.•••··• . . << 37. Wagner ER, Zhu G, Zhang BQ, Luo Q, Shi Q, Huang E, Gao Y, Gao JL, Kim SH, Rastegar F, Zuo GW, Bi Y, Luo J, Luo X, Huang J, Deng ZL, Reid RR, Luu HH, Haydon RC, He TC. Therapeutic potential of theWntsignaling pathway in bone metabolic disorders. Current Moiecular Pharmacology 2011; 4(1): 14-25. 38. Smartt Jr. JS, Elliott R, Re.i d RR, Bartlett SP .. Analysis of thedifferences in the cranial base and facial skeleton of patients with lambdoid synostosis and defo rmational plagiocephaly. Plastic and Reconstructive Surgery 2011; 127(1): 303·312. 39. Lee JC*, SpiguelLS*, Shenaq DS, Zhong M, WietholtC, He TC, Reid RR. The role of RANK·RANKL-OPG axis in cranial suture homeostasis. Journal ofCraniofacial Surgery 2011; (in ptess--*both authors contributed equally to this work). Case ID: 110503459 Control No.: 13041685 FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 Russell R. Reid, MD PhD 7 40. Luther G, Wagner ER, Zhu G, Kang Q, Luo Q, Lamplot J, Bi Y, Luo X, Luo J, Teven C, Shi Q, Kim SH, Gao JL, Huang E, Yang K, Rames R, Liu X, Li M, Hu N, Liu H, Su Y, Chen L, He BC, Zuo GW, Deng ZL, Reid RR, Luu HH, Haydon, RC and He TC: (2011) BMP-9 Induced Osteogenic Differentiation of Mesenchymal Stem Cells: Molecular Mechanism and Therapeutic Potential Current Gene Therapy [in press] Submitted Manuscripts and Manuscripts in Preparation. 1. Stephanie H Kim, Guowei Zuo, Bai-Cheng He, Ning Hu, Yang Bi, Jinyong Luo, Qing jo, Lan Zhou, luang, Ke Yang, Jian-L lunjiang He, Jong Kyung Park, Jiayi Huang, Gai Zhu, Yuxi Su, Xing Liu, Linyuan Wang, Hong Liu, Liang Chen, Qiong Shi, Quan Kang, Zhong-Liang Deng, Regulates Bone Mineral Density and Glucose Metabolism, (submitted). 2. Qiong Shi, Yaguqng, Jinyong Luo, Gaohui Zhu, Liang Chen, Bai-Cheng He, Guo-Wei Zuo, Jiayi Huang, Qing Luo, Stephanie H. Kim, Enyi Huang, Jian-Li Gao, Ke Yang, ag Zhang, Chuan He: Cysteine-rich with EGF-like domains 2 (CRELD2) Plays an Important Role in BMP9-induced Osteogenic Differentiation of Mesenchymal Stem Cells and Bone Formation, (submitted). 3. Liang Chen, Wei Jiang, Bai-Cheng He, Guo-Wei Zuo, Qing Luo, Bing-Qiang Zhang, Christian Wietholt, Qiong Shi, Enyi Huang, Yanhong Gao, Jian-Li Gao, Stephanie H. Kim, Ke Yang, Eric R. Wagner, Jinyong Luo, Xiaoji Luo, Yang Bi, Yuxi Su, Bo Liu, Jikun Shen, Xing Liu, Ning Hu, Mi Li, Linyuan Wang, Russell R. Reid, Hue H. Luu, Zhong-Liang Deng, Tong-Chuan He* and Rex C. Haydon* Insulin-like Growth Factor-1 (IGF1) acts synergistically with Bone Morphogenetic Protein-9 (BMP9) during osteogenesis. Molecular Therapy (in preparation) (*co-corresponding authors Invited Reviews. Reid RR. Facial growth and timing of surgical intervention. Clinics in Plastic Surgery. 2007; 34(3): 357-367. Book Chapters. 1. Reid RR. Lip Reconstruction. Chapter in Plastic and Reconstructive Surgery: Board Review. Lin S. and Hijjawi J., eds. McGraw-Hill, Inc. 2005. 2. Percec I, Reid RR, Bartlett SP. Distraction of the Craniofacial Skeleton: Experience at the University of Pennsylvania. Chapter in Liu C, ed. Distraction Osteogenesis of the Craniomaxillofacial Skeleton. The People’s Hygiene Publisher, Beijing, China. 2005. 3. Reid RR. Head and Neck. Chapter 4 in Essentials for Students. American Society of Plastic Surgeons/Plastic Surgery Educational Foundation, 7th ed. (2007). 4. Reid RR. Skin and Subcutaneous Lesions. Chapter 3 in Essentials for Students. American Society of Plastic Surgeons/Plastic Surgery Educational Foundation, 7th ed. (2007). FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 Russell R. Reid, MD PhD 8 5. Reid RR, Lu L, Dumanian GA. Pediatric pressure sores. Chapter 59 in Bentz ML, Bauer BS, Zuker RM, ed. Principles and Practice of Pediatric Plastic Surgery, Quality Med. Publishing, Inc.; St. Louis, 2008. 6. Gottlieb LJ, Reid RR. Multi-Staged Autologous Reconstruction of the Face. Book Chapter in Semionow, M, ed. The Know-How of Facial Transplantation, in press. 7. Lee JC, Reid RR, Gottlieb LJ. Pediatric Trunk Defects. Book Chapter in Neligan P., ed. Plastic Surgery 2011,3rd ed., in press. 8. Seitz IA, Teven CM, Reid RR. Repair and Grafting of Bone. Book Chapter in Neligan P. ed. Plastic Surgery 2011,3rd ed., in press. Scientific Papers and Scientific Exhibits Shenaq D, Teven C, He TC, Reid R. The osteogenic characteristics of immortalized calvarial cells. Oral presentation at the 3rd European Plastic Surgery Research Council (Hamburg, Germany), 2011. Spiguel LR, Lee J, Sheine Y, He TC, and Reid RR. Osteoimmunology and cranial suture biology. Oral presentation at the 54th Plastic Surgery Research Council (Pittsburgh, PA) and Poster presentation at the 16th Annual Charles B. Huggins Research Council, University of Chicago (Chicago, IL), 2009. Seitz 1A, Spiguel LR, Teven CM, Wietholt C, Januszek M, Haydon RC, Luu HH, He TC, Reid RR. The differential effects of BMP-2 and BMP-9 in critical-sized, murine cranial defects. Oral presentation at the XHIth Congress of the International Society of Craniofacial Surgeons, Oxford, UK and Poster presentation at the 16th Annual Charles B. Huggins Research Council, University of Chicago (Chicago, IL) 2009. Teven CM, Su Y, Bi Y et al. (Reid RR senior author). A novel delivery system of pulsed electromagnetic fields accelerates osteogenic differentiation of mesenchymal stem cells. Oral presentation at the 54th Plastic Surgery Research Council (Pittsburgh, PA) and Poster presentation at the 16th Annual Charles B. Huggins Research Symposium, University of Chicago (Chicago, IL), 2009. Mou S, Sharff K, Song WX, He TC, Reid RR. Enhanced osteogenic capacity of bone precursor cells co-transduced with human telomerase and bone morphogenetic protein 9. Oral presentation at the 53rd Plastic Surgery Research Council (Springfield, IL) and Poster presentation at the 15th Annual Charles B. Huggins Research Symposium, Department of Surgery, University of Chicago, Chicago, IL 2008. Reid RR, Selber J, Chike-Obi C, Bartlett SP. Demographic Shift in the Non-syndromic Craniosynostoses. Scientific paper presented at the 1st Annual Whitaker Lectureship, University of Pennsylvania, Philadelphia, PA 2006. Smartt JM, Reid RR, Singh DJ, Bartlett SP. True Lambdoid Craniosynostosis: Results of Surgical Therapy. Scientific paper presented at the XI International Society for Craniofacial Surgeons Biennial Meeting, Queensland, Australia, 2005. FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 Russell R. Reid, MD PhD 9 Reid RR, Margulis A, Patel PK. Resorbable versus Titanium Fixation of Le Fort I Osteotomies in the Cleft Population. Scientific paper presented at the Midwestern Association of Plastic Surgeons Meeting, Chicago, IL, 2005 (Best Clinical Paper Award) Reid RR, Roy N, Mogford JE, Zimmerman H, Lee C, Mustoe TA. Retroviral Delivery of a Dominant Negative TGF Beta Receptor II Mitigates Scar in A Rabbit Model of Scar Hypertrophy. Research paper award, Chicago Society of Plastic Surgeons - 2005. Scientific paper presented at the Wound Healing Society Meeting, Atlanta, GA, 2004. Reid RR, Bauer BS, Fine NA. The Role of "Double Delay” of Expanded Flaps in Pediatric Reconstruction. Scientific paper presented at the Midwestern Association of Plastic Surgeons Meeting, Chicago, IL, 2004. Reid RR, Said HK, Haines 111 GK, Few JW. The Upper Eyelid: The Introduction of the Septal Extension. Scientific paper presented at the Midwestern Association of Plastic Surgeons Meeting, Chicago, IL, 2004. Reid RR, Dumanian GA. Panniculectomy andThe Separation of Parts Hernia Repair: A Solution for the Large Infraumbilical Hernia in the Obese Patient. Scientific paper presented at the Midwestern Association of Plastic Surgeons Meeting, Chicago, IL, 2004. Reid RR, Greve SD, Casas LA. The Effect of Zafirlukast (Accolate) on Early Capsular Contracture in the Primary Augmentation Patient: A Pilot Study. Poster presented at the American Society of Plastic Surgery, San Diego, CA, 2003. Reid RR, Said HK and Few, JW. The Upper Eyelid: Relevant Septal Anatomy in Aesthetic Surgery. Scientific paper presented (by JWF) at the American Society of Aesthetic Plastic Surgery, Boston, MA, 2003. Reid RR, Said HK, Mogford JE and Mustoe TA. The Future of Wound Healing: Surgical Models in Transgenic Mice. Scientific paper presented at the American College of Surgeons, San Francisco, CA, 2002. Reid RR, Mogford JE, Zhang M, Wakim, B., Carroll MC, Mustoe TA. The Binding of Natural IgM to Hypoxic Endothelium: Implications in Ischemia-Reperfusion Injury. Poster presented at The Wound Healing Society, Baltimore, MD, 2002 Reid RR, Shohet JS, Pemberton PA, Carroll, MC: Localization of C3-IgG covalent binding site. Poster presented at Federation of American Societies for Experimental Biology, Anaheim, CA., 1994 Reid RR, Shohet JS, Pemberton PA, Carroll, MC: Localization of C3-IgG covalent binding site. Scientific paper presented at XVth International Complement Workshop. Kyoto. Japan. 1993 Invited Visiting Professorships/Lectures/Grand Rounds INDEX NO. 026910/2012 FILED FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 '. ■;:S CivilAdministration- 1 ir- :: N. ESSOUNNI Russell R. Reid, MD PhD 0 Co-Chair, Basic Craniomaxillofacial Principles Course, AO North America, Chicago, IL, 2012. Invited Faculty, American Society of Plastic Surgeons Oral and Written Board Preparation Course. "Implants and Biomaterials.'’ Chicago, IL, 2011. Advances in Pediatrics 2011 Symposium. Advocate Lutheran General Hospital/Advocate Lutheran General Children’s Hospital Cleft Lip and Palate, Park Ridge, IL, March 11,2011. Grand Rounds, Section of Pediatric Surgery, University of Chicago Medical Center. Wound Healing, Chicago, IL, November 9, 2010. Session Co-Chair, Research, Plastic Surgery 2010, American Society of Plastic Surgeons, Toronto, ON, Canada, October 4, 2010. Session Co-Chair, Craniofacial Research, 2nd European Plastic Surgery Research Council, Hamburg, Germany, August 28, 2010. Session Co-Chair, Craniofacial Biology 2. 67th Annual Meeting, American Cleft Palate- Craniofacial Association, Dallas, TX, March 19, 2010. Grand Rounds, Department of Pediatrics, University of Chicago Medical Center. The Nonsyndromic Craniosynostoses. Chicago, IL, March 12, 2009. Grand Rounds, Section of Neurosurgery, University of Chicago Medical Center. The Syndromic Craniosynostoses. Chicago, IL, January 7, 2009. Reid RR. Mandibular Fractures. National Medical Association: 2008 Annual Convention & Scientific Assembly, Atlanta, GA, July 28, 2008. Reid RR. Mandibular Distraction Osteogenesis. National Medical Association: 2008 Annual Convention & Scientific Assembly, Atlanta, GA, July 28, 2008. Smartt JM, Reid RR, Singh DJ, Bartlett SP. Lambdoid Craniosynostosis vs. Positional Plagiocephaly: Diagnosis and Treatment Options. Panel Session: Interdisciplinary Problem-Solving in Pediatric Neurosurgery and Craniomaxillofacial Surgery (ImproMed) (presented by SP Bartlett), Phoenix, AZ, 2008. Grand Rounds, Department of Pediatrics, Advocate Lutheran General Hospital. The Syndromic Craniosynostoses. Park Ridge, IL, December 18, 2007. Grand Rounds, Midland Memorial Hospital. Abdominal Wall Reconstruction, Midland TX. May 16, 2007. FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 ■ mi Si I Russell R. Reid, MD PhD 1 1 Moderator, Faculty Session. 14th Annual Charles B. Huggins Research Symposium, University of Chicago, Department of Surgery, May 5, 2007. Grand Rounds, Department of Pediatrics, University of Chicago. The Syndromic Craniosynostoses: Reconstructive Approaches. January 18, 2007. Instructor, ASMS BASIC MAXILLOFACIAL PRINCIPLES & TECHNIQUES. Chicago, IL August, 2006. Controversies in Pediatric Craniofacial Trauma. Synthes CMF Intermediate Training Curriculum, Paoli, PA 2005, 2006. Craniosynostosis. Synthes CMF Intermediate Curriculum, Paoli, PA 2005, 2006. Distraction Osteogenesis. Synthes CMF Intermediate Curriculum, Paoli, PA 2005, 2006. Positional Plagiocephaly versus True Lambdoid Synostosis. Grand Rounds, Brown University Division of Plastic Surgery, 2005. Positional Plagiocephaly versus True Lambdoid Synostosis. Grand Rounds, University of Chicago Section of Plastic Surgery, 2005. Sponsored Scholarly Activities ADA Carol Kuckein Grant, 2011. Proposal Title: "The Use of a Novel, Three-Dimensional Biocompatible Scaffold to Deliver Osteoprogenitor Cells to a Critical-Sized Calvarial Defect.” Awardee: Mr. Chad M. Teven, MSIV, Pritzker School of Medicine. PI: Russell R. Reid AOA Carol Kuckein Grant, 2010. "Proposal Title: The Differential Effects of Cellularly Engineered BMP-2, BMP-9 and RunX2 on Bone Healing in Murine Critical-Sized Calvarial Defects." Awardee: Ms. Deana Shenaq, MSIV, Pritzker School of Medicine. PI: Russell R. Reid "The Role of RANK/RANKL/OPG Axis in Cranial Suture Homeostasis." Oral Presentation: Dr. Justine Lee, Resident, Plastic Surgery, Univ. of Chicago. PI: Russell R. Reid. Plastic Surgery 2010, Toronto ON, Canada, October 2010 and 3rd International Conference on Osteoimmunology, Interactions of the Immune and Skeletal Systems. Santorini, Greece, June 2010. Research Support- Current Support. P.I. Reid RR. NIH/NIDCR K08 Clinical Investigator Award/Mentored Research Award 1-K08DE020140-01 (9/1/2009-8/31/2014): Differential Effects of BMPs on Healing of Craniofacial Defects. ($123,550 per annum; project period 5 years). FILED: SUFFOLK COUNTY CLERK 08/30/2022 03:55 PM INDEX NO. 026910/2012 NYSCEF DOC. NO. 160 RECEIVED NYSCEF: 08/30/2022 w aaamt P.I. Reid RR. Plastic Surgery Education Foundation (PSEF) Seed Grant (7/1/2010- 6/30/2011) Principal Investigator: The Role of RANK/RANKL/OPG Axis in Cranial Suture Homeostasis ($10,000). Past Support. P.I. Reid RR. 3M Wound Healing Research Award (2001) The Role of Natural Antibodies in Ischemia-Reperfusion Injury ($5,000). P.I. Few Jr., JW. Co-P.I. Reid RR. Wound Healing Research Grant, Besin International Ltd. (2003) Co-Investigator ($250,000+). P.I. Reid RR. Children's Memorial Research Foundation, Inc. (2004) Genetic Expression of the Developing Murine Auricle: Implications in Congenital Ear Deformities ($3,600). P.I. Reid RR. Maxillofacial Surgeons Foundation of the American Society of Maxillofacial Surgeons Research Award (2006) Acceleration of Mandibular Distraction-Associated Bony Regenerate Healing by Electrical Field Stimulation ($3,750). P.I. Reid RR. Plastic Surgery Education Foundation (PSEF) Basic Research Grant (2008). Differential Effects of Human Telomerase and Bone Morphogenetic Proteins on Bone Healing in Murine Models. ($ 5,000 #BRG48-08). P.I. Reid RR. Advocate Lutheran General Hospital Partners Endowment (2008). Principal Investigator: The Development and Implementation of a Computerized Craniofacial Database ($15,000). P.I. Reid RR. Komedyplast/American Society of Craniofacial Surgeons Craniofacial Research Grant Award (2009). Osteoimmunology and Suture Biology. ($5,000). P.I. Reid RR. Maxillofacial Surgeons Foundation of the American Society of Maxillofacial Surgeons Research Award (2009) The Use of Pulsed Electromagnetic Fields for the Enhancement of the Consolidation Period of Distraction Osteogenesis ($3,000). Mentoring and Supervision of Medical Students. Name: Shanshan Mou, M.D., M.S. Duration: June 2007 - August 2007 Research Project: Enhanced Osteogenic Capacity of Bone Precursor Cells Co-transduced with Human Telomerase and Bone Morphogenetic Protein 9. Awards/Distinctions: Recipient of 2007 Summer Research Program of Pritzker School of Medicine; Recipient of the Basic Science Excellence Award, 2007 Summer Research