Exhibit,Appendix: Patsy Young v. Aventis Inc., Avon Products, Inc., Block Drug Company, Inc. (Sued Individually And As Successor-In-Interest To The Gold Bond Sterilizing Powder Company A/K/A The Gold Bond Company), Block Drug Corporation (Sued Individually And As Successor-In-Interest To The Gold Bond Sterilizing Powder Company A/K/A The Gold Bond Company), Brenntag North America, Inc. (Sued Individually And As Successor-In-Interest To Mineral Pigment Solutions, Inc. And As Successor-In-Interest To Whittaker Clark & Daniels, Inc.), Brenntag Specialties, Inc. F/K/A Mineral Pigment Solutions, Inc. (Sued Individually And As Successor-In-Interest To Whittaker Clark & Daniels, Inc.), Charles B. Chrystal Company, Inc., Chattem, Inc. (Sued Individually And As Successor-In-Interest To Block Drug Corporation, Successor-In-Interest To The Gold Bond Sterilizing Powder Company A/K/A The Gold Bond Company), Colgate-Palmolive Company, Cyprus Amax Minerals Company (Sued Individually, Doing Business As, And As Successor To American Talc Company, Metropolitan Talc Co. Inc. And Charles Mathieu Inc. And Sierra Talc Company And United Talc Company), Cyprus Mines Corporation, Glaxosmithkline Llc (Sued Individually And As Successor-In-Interest To Block Drug Corporation, Successor-In-Interest To The Gold Bond Sterilizing Powder Company A/K/A The Gold Bond Company And As A Successor-In-Interest To Novartis Corporation And NOVARTIS CONSUMER HEALTH INC.), Gsk Consumer Health, Inc. F/K/A Novartis Consumer Health Inc. F/K/A Ciba Self-Medication, Inc., Insight Pharmaceuticals Corporation, A Subsidiary Of Prestige Brands Holdings, Inc., Insight Pharmaceuticals Llc, Macy'S Inc. F/K/A/ Federated Department Stores, Inc. (Sued Individually And As Successor-In-Interest To Twin Fair, Inc.), Novartis Corporation (Sued Individually And As A Successor-In-Interest To Ciba-Geigy Corporation And Its Subsidiaries Ciba Consumer Pharmaceuticals And Ciba Self-Medication, Inc.), Novartis Pharmaceuticals Corporation (Sued Individually And As Successor-In-Interest To Ciba-Geigy Corporation And Its Subsidiary Ciba Consumer Pharmaceuticals), Prestige Brands Holdings, Inc., Prestige Consumer Healthcare Inc. F/K/A Prestige Brands, Inc., Sanofi-Aventis U.S. Llc (Sued Individually And As Successor By Merger To Aventis Pharmaceuticals Inc.), Sanofi Us Services, Inc., Whittaker Clark & Daniels, Inc.

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                      EXHIBIT 63
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          MASTER EXHIBIT 143
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                                               '""-·   _,   ....   ,

                                                       of The City UniVersity of New· York

                                                                                                           ARCHIVES
                                                                                                         MOu~r SI1'4AI
                         To:     Dean Thomas C. Chalmers                        Doto:   March 17, 1976


                         From: Dr. Arthur M. Langer                             Subject: The ongoing Talc Study in the
                                                                                        Environmental Sciences Laboratory.



                               Following our telephone conversation of Wednesday, March 17th, I am
                               herein submitting to you, as accurately as memory permits, the involve-
                               ment of our Laboratory with the analysis of talc-containing consumer
                               products.

                            In December of 1968, Dr. Selikoff and I were invited to the Food and
                            Drug Administration to participate in a seminar before the Division of
                            Pharmacology and Toxicology. We presented materials under the title
                           "current studies on pulmonary fibrous mineral microparticles - potential
                            contribution of talc:' At the seminar we discussed our studies involving
                            the fiber content of lung tissues obtained from 3 1 000 consecutive autopsies
                           in New York City; the biological hazards associated with the inhalation of
                           asbestos; preliminary data ~~ich suggested that some of theselung fibers were
                           asbestos fibers; the natural contamination of talcum products with fibrous
                           minerals (including asbestos); the potential hazards associated with in-
                           halation of talc dust. If memory serves me correctly this was not the
                           first time this subject matter was broached with FDA. Some members of
                           Food and Drug were present at a meeting a year earlier, in Cincinnati,
                           Ohio, in which the asbestos problem was openly discussed at a governmental
                           meeting. It was because of this meeting, and the ensuing discussions,
                           that we were invited to Washington for the seminar. (See Appendix No. 1,)
                           Talc research, for us, was put on a "back burner" for future study. We
                           continued at intervals to examine consumer products and observed that
                           they contain fibrous minerals which when analyzed demonstrated them to
                           be asbestos.

                            In August, 1971, our group was invited to a discussion at the Food and
                            Drug Administration concerning the asbestos content of consumer tales.
                          ·A nUmber of individuals were present representing various areas of society.
                            Dr. Selikoff spoke on the biological significance of asbestos and I pre-
                           ··sented some information concerning the analytical methodology required for
                            asbestos analysis. (See Appendix No. 2,) On page 5 of this document,
                            paragraph 4 reflects our findings concerning asbestos contents of Johnson
                           & Johnson tales.

                           In September, 1971, we began, in a more formal manner, the study of the
                           asbestos content p{( conswner tales. We prepared a study proposal for the
                           Environmental Prqteetion Administration outlining a study for the deter-
                           mination Of the fiber contents of consumer tales sold in New York City.
                          (See Appendix No. 3.) No funds were available for this study and we were
                           so informed. However, we formulated in our own minds the outlines of
                           a consumer talcum study.



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                                                                                                            EXHIBIT
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                 Dean Thomas c. Chalmers               -2-        March 17, 1976




                 In February, 1972, our group was invited down to the Food and Drug
                 Administration to discuss a number of problems. Ostensibly, we dis-
                 cussed the occurrence of asbestos in parenteral drugs.      It is my be-
                 lief that at this meeting we again broached the subject of asbestos
                 contamination of consumer tales. (See Appendix No. 4.)

                In late 1972 and early 1973, I was approached by Dr. Morris Kleinfeld,
                of the N.Y.S. Department of Labor, who had been studying talc miners
                and millers in New York State. He is a recognized authoritY in this
                area and his publications have received wide attention. He and his
                colleagues were the first to epidemiologically establish the association
                between fibrous talc exposure      and excess human malignancies.    He approached
                me to study the mineral content of tales mined from the Balmat-Edwaids
                mining area of New York State. I collaborated with hband one of his
                colleagues and a joint publication resulted from our efforts. (See
                Appendix No. 5.) During this study we developed the methodology for x-ray
                diffraction analysis of talc, and the electron beam instrumentation re-
                quired for the analysis of submicroscopic fibers in talc samples.

                During this time, we began to purchase samples of talc products in New
                York City.     we were not funded to do this research so that we had an
                extremely lim.i ted budget for "cash outlay."    we requested individual
                members of our Laboratory to bring in any "-tales that they might have
                in their medicine cabinets at home" to supply us with some materials.
                At this time I submitted to the Public Health Service a grant application
                entitled "Asbestos content of consumer talcum products."      (See Appendix
                No. 6.)     We again outlined in very great detail an analytical procedure
                for the analysis of consumer tales for their asbestos contents.       The
                methodology for talc analysis was worked out at this time and we believe
                the research warranted support because of its importance.      Unfortunately,
                although the grant was approved (favorably recommended) the relative
                priority number was not great enough to have it funded.

                We continued with our work concerning the analysis of consumer talcum
                products. In May of 1973, several of my colleagues and I were invited
                to a symposium on talc in Washington, D.C.      This was sponsored by the
                Bureau of Mines and pertained to various aspects concerning the biologi-
               .. cal hazards associated with the talc mining industry.    I presented
                materials concerning the nature of talc mineralogically and reported the
                occurrence of asbestos fibers in the lung tissues of a workman exposed
                to talc dust.      This circular of the Bureau of Mines has been used by the
                ne~media    many    times and from it many inquiries had been directed to us.
                (See Appendix No. 7.)

               Still without sig~i'ficant research support, other than "stealing time"
               from other projec~s, we continued our analyses of consum~r tales. In
               the spring of 1974, my colleagues and I were invited·to a microscopy
               symposium in New York City to discuss the identification and quantita-
               tion of asbestos fiber in a range of media. or. Rohl and I have reported
               results concerning the identification and quantitation of asbestos in
               talc.      (See Appendix No. 8.)   These papers were submitted for publication
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                 Dean Thomas c. Chalmers          -3-          March 17, 1976




                 in the Environmental Health Perspectives. This paper has become a
                 standard methodology in that we have had requests from the
                 Philips Electronics Corporation for reprints to be used in their teaching
                 seminars in Mt. Vernon. This paper repre.sents almost one year of "bench"
                 time. This is one of our basic techniques in· the analysis of consumer
                 talcum products.

                In order to properly "round outn our studies we in vi ted several of _our
                colleagues in Great Britain to join with.us in mutual collaborative
                efforts. We decided that our studies would be strengthened if we knew
                more about the bulk chemistry and trace metal contents of these mate~ls.
                Dr. Donald R. Bowes, Professor of Petrology and Geochemistry from The
                University, Glasgow, consented to work with us. His laboratory furnishes
                our studies with complete chemical analyses of materials we send to him.
                Complete analyses of British consumer talcum products may be found in
                the paper included in Appendix No. 9. Some ten major oxides and 17 trace
                metals are routinely analYzed. The samples are run in duplicate and
                triplicate and if "mismatches'' are obtained, the analyses are thrown
                out and done over again. Or. Bowes has 20 years of experience in the
                geochemistry field and his reputation is excellent.

                 My colleagues and I were invited to present a paper at the British
                 Occupational Hygiene Society's meeting, held in Edinburgh in September of
                 1975. (See Appendix No.9.)       In the session called "talc" Dr. Pooley and
                 I w~re listed to present a paper entitled "chemical, physical and mineralogi-
                 cal characteristics of tales." The authorship and titles were later changed,
                 in which Dr. Pooley was made senior author and the title was .amended to
                11
                   Mi:neralogy and chemistry of British talc and consumer talcum products.''
                This paper was withdrawn by Dr. Pooley two days prior to the conference
                start. We ~nclose·an 18-page paper which was to be presented. The reasons
                for or. Pooley's withdrawal of this paper are many and I shall be happy to
                discuss these with you in private. He was subjected to personal and pro-
                fes~ional pressures and industry harasssent.     We respected Dr. Pooley's
                wis~es at the time of the conference and allowed him to withdraw it. This
                manUscript is being resubmitted to a different British journal for publi-
                cation. Or. Rohl has the correspondence connected with the withdrawal of
                the paper and the subsequent request for its sUbmission to an appropriate
                journal in Great Britain.

                These doc~ents, and the above statements, more or less outline our inter-
                est in talc and consumer talcum products. t~ colleagues and I have been
                studying this problem area for a number of years. A number of press re~
                leases have appeared over the past several years generally as the result
                of wideSpread ip.terest i~ this subject area. I cannot count the ntunber
                of times I have.been approached by individuals in the journalism field
                with questions concerning asbestos contents of consumer tales. Many
                occasions, both iri personal contact and by telephone, have prese~ted them-
                selves in which this subject area was broached. My colleag-ues find tllis
                to be "old hat" not necessarilY reflecting that it is unimportant, but
                rather it is just~~ to us.
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                  Dean Thomas   c.   Chalmers    -4-           March 17, 1976




                 The consumer tales (United States) have been studied with identical
                 methods as the British tales. The paper has been accepted for publi-
                 cation in Environmental Research. A revised pre-publication manuscript
                 will be· shortly forwarded to your office.
                                                                          !
                 If you have any further questions concerning              als I shall
                 be very happy to answer them.




                                                           ~~~TL~.g   r, Ph.D.
                                                                Professor of Yinera ogy
                                                       Head, Physical Sciences Section



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